Michał Piasecki (Uniwersytet Medyczny w Białymstoku, “CRISPR in medicine”), Ada Frankowska (UJ, “Botox for ... How the facial feedback works”) oraz Marek Treppner (GUMed, “On the red pandas and meditation”).
On May 27-June 1, 2018, international educators and organisations that support international
The visit was organised as part of the Erasmus+ programme. During her stay, prof. ... Wach delivered lectures for students of Nursing and anaesthesiology nurses working in hospitals in the ... There was also an opportunity to meet the Deputy Director for Nursing at University Clinical Centre in
Graduates of the Faculty of Pharmacy 2012-2018 received their diplomas on May 11, 2018, at the Auditorium
Konferencja odbędzie się w dniach 24-26 maja br. w Gdańsku.
Streszczenie Background Bacillus subtilis spores can be used for presentation of heterologous proteins ... genome to express a protein of interest as a fusion with spore-coat protein, and non-recombinant, based on ... So far only single proteins have been displayed on the spore surface. ... Results We have used a combined approach to adsorb and display FliD protein of Clostridium difficile on ... such recombinant IL-2-presenting spores with adsorbed FliD protein might be an interesting candidate for
Materials and methods This study was based on the model of bacterial peritonitis in rats induced with ... For the 20 animals in the studied group, bacterial fluid was applied into the abdominal cavity together ... After 5 weeks, the animals were operated on again, and the meshes, the peritoneal fluid and, if present ... , any granulomas were taken for bacterial cultivation. ... In 9 out of 10 rats that were exposed to the rolled mesh for 5 weeks, the colonisation of meshes with
Antigens and enzymes have been successfully exposed on the surface layers of the Bacillus subtilis spore ... multi-subunit enzymes with a central role in the virulence of various bacterial pathogens and necessary for ... Results We expressed UreA from H. acinonychis on the B. subtilis spore coat by using three different ... coat proteins CotC allows the highest efficiency of expression, whereas CotB is the most appropriate for ... the display of heterologous proteins on the spore surface.
The study describes the influence of the health condition of laboratory animals used in experiments on ... It also presents a classification of animals into health categories depending on their microbiological ... Moreover, the study describes general rules compliant with European standards for monitoring the health ... of laboratory animals, including a detailed register of detected pathogens specific for mice and rats ... Numerous pathways of disease spread and their influence on the course of the experiment are pointed out
Protein expression was examined by immunohistochemistry on tissue microarrays. ... Kaplan-Meier curves for disease-free survival (DFS) and overall survival (OS) were compared using F-Cox ... Results On average, mRNA expression of TWIST1, SNAIL and SLUG was significantly higher in LNM compared ... to PT (P less than 0.00001 for all). ... Thus, molecular profiling of LNM may be used as surrogate marker for aggressiveness and metastatic potential
Streszczenie Autoclaving is the current method of choice for sterilization of diets for specified-pathogen-free ... phytoestrogens (S) or with casein (C ), and a commercial autoclavable (SN) diet, were autoclaved at 121°C for ... 20 min (T1) or at 134°C for 10 min (T2).
concern, especially when the vitamin composition is highly complex, as is the case with feed designated for ... combining microemulsion electrokinetic chromatography (MEEKC) with liquid–liquid extraction was developed for ... CONCLUSION It was proved that the proposed MEEKC method was sufficiently specific and sensitive for screening
Streszczenie The technology of display of heterologous proteins on the surface of Bacillus subtilis ... spores enables use of these structures as carriers of antigens for mucosal vaccination. ... there are no technical possibilities to predict whether a designed fusion will be efficiently displayed on ... Moreover, we used these spores for mucosal immunization of mice.
Tomasz Bogusławski for the needs of the Polish national program PolSenior2, coordinated by the Department ... The projects could be seen at the exhibition in the Main Library and visitors could vote for their favorite ... The announcement of the results of the competition took place on May 12th. ... Marcin Gruchała, Vice-Rector for Development and Education prof.
Streszczenie Background Experiments on cancer cell lines and animal models indicated that alteration ... The overall survival time for patients with II tumor, node, metastasis system (TNM) stage disease and ... survival rate of patients with TNM stage II disease and T4 lesion was significantly lower (P = .0005) for ... Conclusions The assessment of NDRG1 expression offers valuable prognostic information for patients with ... colorectal cancer, especially for those with stage II disease.
However, it was considered that, SDS-CGE seems to have a potential to be the alternative, efficient tool for ... the separation of tissue proteins based purely on their molecular weights.
Here, we demonstrate the mechanism of C-1311 inhibitory action on novel targets: hypoxia-inducible factor ... Continuous low C-1311 dosing (8 mg/kg/day for 5 days) gave similar inhibition of angiogenesis (80%), ... C-1311 (8 mg/kg/day for 9 days), completely abrogated vascularization of the alginate implants.
CD73 expression was examined by immunohistochemistry (IHC) on tissue microarrays, using antihuman mouse ... Multivariate analysis for disease-free survival revealed correlation with tumor size and CD73 status.
Streszczenie The endospores of Bacillus subtilis are now widely used as a platform for presentation ... record and high resistance to harsh environmental conditions can be considered as potential vehicles for ... We show for the first time the successful application of two types of recombinant spores, one carrying
The method was applied for quantification of vitamins B1, B2, B5, B6, B9, C, and H in novel feed for ... The simplicity of the procedure should make it highly useful for feed quality control in husbandry and
For plasma samples spiked with the isoprostanes at a level of 200 pg/mL each, the method imprecision ... hydroperoxide (TBHP), a model inducer of oxidative stress, or to antitumor drug doxorubicin (DOX) known for
Streszczenie Current progress in research on vaccines against Helicobacter pylori emphasizes the significance
of HER heterodimers in tumor progression and confirm earlier data that HER2 is the preferred partner for
Methods Snap-frozen tumor samples from 322 consecutive stage I–III breast cancer patients were analyzed for
Material for investigation was DNA isolated from tumours of 138 patients diagnosed with breast cancer