- Objawy tych chorób są bardzo różnorodne, od gorączki i stanów podgorączkowych, przez przewlekłe
Pod nazwą „Leśnik i zwierzęta” edukatorki z Nadleśnictwa Wejherowo – Izabela Kashyna-Pleskot i Katarzyna ... przeprowadziły pierwsze zajęcia edukacyjne, w których uczestniczyli najmłodsi pacjenci przebywający pod
., Anita Kornicka Ph.D. and prof. ... ., members of the Faculty Council, guests and graduates’ families. ... After Rector and Dean’s speeches, 88 graduates made a solemn pledge and received diplomas. ... Graduates with the best results were awarded congratulatory letters and book prizes funded by the Gdańsk
Pod opieką dr hab.
brzusznej w procesie optymalizacji leczenia przepuklin” realizowanego wspólnie z Politechniką Gdańską pod
the influence of the health condition of laboratory animals used in experiments on the credibility and ... a classification of animals into health categories depending on their microbiological purity: germ-free ... animals, specific pathogen-free animals and conventional animals. ... be fulfilled by animal quarters with a sanitary-hygienic barrier in order to keep specific pathogen-free ... the course of experiments and should be regularly monitored.
17 polysomy in patients with early breast cancer and to correlate the status of these alterations with ... the prognostic significance expressed as patients’ clinical features and survival. ... TOP2A amplification and deletion assessed by FISH were found in 23% and 7% of the tumours, respectively ... , and by qPCR in 31% and 11% of the tumours, respectively. ... TOP2A amplification (by qPCR) correlated with shorter disease-free survival (p = 0.03) and overall survival
Streszczenie Antitumor imidazoacridinone C-1311 is a DNA-reactive topoisomerase II and FLT3 receptor ... on novel targets: hypoxia-inducible factor-1α (HIF-1α), vascular-endothelial growth factor (VEGF), and ... In a cell-free system, C-1311 prevented HIF-1α binding to an oligonucleotide encompassing a canonical ... In colon cancer HCT116 and murine melanoma B16/F10 cells, C-1311-induced down-regulation of VEGF, resulted ... Our findings indicate that C-1311 is an effective inhibitor of HIF-1α, VEGF, and angiogenesis and provide
been postulated to play an important role in carcinogenesis, as adenosine promotes tumor progression and ... The study group included 136 consecutive stage I-III breast cancer patients treated between 2001 and ... Survival curves were generated by the Kaplan-Meier method and compared using the log-rank test. ... Positive CD73 expression strongly correlated with longer disease-free survival (hazard ratio=0.26; 95% ... Multivariate analysis for disease-free survival revealed correlation with tumor size and CD73 status.
Results A high TOP2A gene dosage was found in 94 tumors (29%)—32% and 27% of HER-2 and HER-2− tumors, ... The mean TOP2A gene dosages in the HER-2 and HER-2− groups were 1.49 ± 1.03 and 1.09 ± 0.35, respectively ... High TOP2A gene dosage had an inverse prognostic impact in terms of shorter disease-free survival (DFS ... ) and overall survival (OS) times in the entire group and in both the HER-2− and HER-2 subgroups. ... -2− tumors and has a strong adverse prognostic impact.
Streszczenie Background The aim of this study was to evaluate whether the type of the mesh and proper ... surgical technique can influence the outcome of a tension-free hernia repair in a contaminated filed ... Materials and methods This study was based on the model of bacterial peritonitis in rats induced with ... a mixture composed of Escherichia coli and Bacteroides fragilis. ... After 5 weeks, the animals were operated on again, and the meshes, the peritoneal fluid and, if present
Streszczenie Autoclaving is the current method of choice for sterilization of diets for specified-pathogen-free ... Chemical composition, selected water- and fat-soluble vitamins, and acrylamide were analysed in all non-autoclaved ... The contents of NDF and N-NDF were increased by T2 and T1; the change was the largest in the SN and the ... The acrylamide concentration increased more in diets autoclaved at T2 than at T1 and in the S and C diets ... Autoclaving the S diet increased the daidzin and genistin contents and slightly reduced the total isoflavone
We evaluated mRNA and protein levels of master EMT regulators: TWIST1, SNAIL and SLUG, protein levels ... , ER and PgR in PT and corresponding LNM. ... Kaplan-Meier curves for disease-free survival (DFS) and overall survival (OS) were compared using F-Cox ... Gene and protein levels of TWIST1, SNAIL and SLUG were highly discordant between PT and matched LNM. ... Increased mRNA expression of TWIST1 and SNAIL in LNM was associated with shorter OS (P = 0.04 and P =
modification of bacterial genome to express a protein of interest as a fusion with spore-coat protein, and ... Results We have used a combined approach to adsorb and display FliD protein of Clostridium difficile ... presented FliD protein with efficiency comparable to FliD-adsorbed spores produced by wild-type 168 strain and ... such dual display technology may be useful in creation of spores simultaneously presenting adjuvant and
Streszczenie The objective of this study was to characterize and compare the water and salt soluble ... proteins from rat liver and muscle by using sodium dodecyl sulphate polyacrylamide gel electrophoresis ... (SDS-PAGE) and sodium dodecyl sulphate polymer-filled capillary gel electrophoresis (SDS-CGE). ... The evaluation and comparison of separations realized with the use of both techniques was done.
Konferencja odbędzie się w dniach 24-26 maja br. w Gdańsku.
Antigens and enzymes have been successfully exposed on the surface layers of the Bacillus subtilis spore ... , but only in a few cases the efficiency of expression and the effective surface display and have been ... Ureases are multi-subunit enzymes with a central role in the virulence of various bacterial pathogens and ... acinonychis on the B. subtilis spore coat by using three different spore coat proteins as carriers and ... compared the efficiency of surface expression and surface display obtained with the three carriers.
Streszczenie Background Experiments on cancer cell lines and animal models indicated that alteration ... This study was undertaken to reveal the prognostic and predictive usefulness of NDRG1 expression determination ... The overall survival time for patients with II tumor, node, metastasis system (TNM) stage disease and ... Moreover, the survival rate of patients with TNM stage II disease and T4 lesion was significantly lower ... be used to select patients with stage II disease who are at increased risk of unfavorable outcome, and
vitamins is not a new area of interest, since these compounds co‐determine the nutritional quality of food and ... feed, a field widely explored in the human and animal diet. ... highly complex, as is the case with feed designated for laboratory animals, representing a higher health and ... consisting of 25 mmol L−1 phosphate buffer (pH 2.5), 2‐propanol, 1‐butanol, sodium dodecyl sulfate and ... octane allowed the simultaneous determination of vitamins A, D, E and K within a reasonable time of
(B2), pyridoxine hydrochloride (B6), calcium pantotenate (B5), ascorbic acid (C ), folic acid (B9), and ... MEKC) method in a single run with the electrolyte solution consisting of 100 mM H3BO3, 5 mM Na2B4O7, and ... The separation was achieved within 8 min. and the detection was performed at 200 nm. ... The method was applied for quantification of vitamins B1, B2, B5, B6, B9, C, and H in novel feed for ... The attained precision level was good with the recoveries between 98.4% and 105.6%.
possibilities to predict whether a designed fusion will be efficiently displayed on the spore surface and ... We show that these spores promote their own phagocytosis and activate both, the J774 macrophages and ... We conclude that the observed effects vary with the type of displayed FliD-spore coat protein fusion and ... seem to be mostly independent of its abundance and localization in the spore coat structure.
jeden projektów logotypów przygotowali studenci Wydziału Grafiki Akademii Sztuk Pięknych w Gdańsku pod
endospores of Bacillus subtilis are now widely used as a platform for presentation of heterologous proteins and ... due to their safety record and high resistance to harsh environmental conditions can be considered as ... that recombinant B. subtilis spores presenting a fragment of the Helicobacter acinonychis UreB protein and ... the first time the successful application of two types of recombinant spores, one carrying an antigen and
for the needs of the Polish national program PolSenior2, coordinated by the Department of Prevention and ... The projects could be seen at the exhibition in the Main Library and visitors could vote for their favorite ... Marcin Gruchała, Vice-Rector for Development and Education prof. ... Jacek Bigda, Director of the Development Project Office Katarzyna Grzejszczak and Project Manager prof
The aim of the study was to analyze the occurrence of abnormal gene copy numbers of all HER oncogenes and ... The HER3 and HER4 amplifications were more common in well differentiated tumors. ... Conclusions Our results indicate a key role of HER heterodimers in tumor progression and confirm earlier ... Deletions of EGFR were associated with unfavorable characteristics, whereas HER3 and HER4 amplifications ... Rhone, Jacek Jassem Źródło: Journal of Cancer Research and Clinical Oncology 2008; vol. 134, nr 2,